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Howard Hughes Medical Institute Holiday Lectures on Science: Of Hearts and Hypertension: Blazing genetic trails - Lecture 2 - "Telltale Genes: Charting Human Disease" by Richard P. Lifton, M.D., Ph.D., 1998-12-01T00:00:00+00:00

 Item — Box: MM-27, Object: 11
Identifier: LE0069
Scope and Contents Lecture by Richard Lifton covering: The human genome contains approximately 100,000 genes organized into chromosomes; Different forms of genes, called alleles, arise by mutations, some of which can lead to disease, or a propensity for disease, in an individual; Many disease-causing alleles have been identified by pinpointing the location of a gene on a human chromosome, followed by molecular cloning; The identification of "disease genes" offers new diagnostic tools, and potential new...
Dates: 1998-12-01T00:00:00+00:00

Howard Hughes Medical Institute Holiday Lectures on Science: Of Hearts and Hypertension: Blazing genetic trails - Lecture 3 - "Heartbreak: Of Mutations and Maladies" by Christine E. Seidman, M.D., 1998-12-01T00:00:00+00:00

 Item — Box: MM-27, Object: 12
Identifier: LE0070
Scope and Contents Lecture by Christine Seidman covering: Heart disease is the leading cause of death in the United States; Hypertrophic cardiomyopathy is a sometimes fatal heart disorder that runs in families; The disease is caused by mutations in one of several genes encoding the proteins that compose the sarcomere, the contractile apparatus of muscle cells; Mice that have been engineered with mutations in genes encoding sarcomere proteins are used as models to explore how gender, exercise and environment...
Dates: 1998-12-01T00:00:00+00:00

Howard Hughes Medical Institute Holiday Lectures on Science: Of Hearts and Hypertension: Blazing genetic trails - Lecture 4 - "The Kidney's Tale: Of Salt and Hypertension" by Richard P. Lifton, M.D., Ph.D., 1998-12-01T00:00:00+00:00

 Item — Box: MM-27, Object: 13
Identifier: LE0071
Scope and Contents Lecture by Richard Lifton covering: High blood pressure, or hypertension, damages blood vessels, contributing to heart attacks, strokes, and kidney failure; Molecular genetic approaches have led to the identification of a number of genes that, when mutated, cause changes in blood pressure; These genes encode ion channels, which are proteins embedded in the cell membrane that control the flux of salt into the blood stream; Mutations that cause hypertension increase the activity of the ion...
Dates: 1998-12-01T00:00:00+00:00

NHGRI Interactive Video Conference Bethesda Site - "Bethesda Disparities" - Dr Francis Collins, MD Anderson Lecture, 2003-06-22T00:00:00+00:00

 Item — Box: MM-27, Object: 14
Identifier: LE0072
Scope and Contents Genomics and health disparieis, Francis Collins (health disparities course) - what causes health disparities, what can we do about them, how to eliminate them, what role does genetics play in health disparities.  Virtually all diseases have genetic components, so understanding that would mean better understanding and ideas how to cure/treat illnesses.  Brief explanation of DNA, genome, Human Genome Project.  New approach (haplotypes) to find genetic components of multifactorial diseases....
Dates: 2003-06-22T00:00:00+00:00

NBC Nightly News; Life Line: Story on Melanoma, Dr. Jeffrey Trent, NHGRI, 2000-08-02T00:00:00+00:00

 Item — Box: MM-27, Object: 15
Identifier: NE0098
Scope and Contents

News report on melanoma - Jeffrey Trent speaks about the discovery, pinpointing genetic changes that make some melanomas spread more quickly.  Scientists target better treatment using genetic knowledge; experimental treatments

Dates: 2000-08-02T00:00:00+00:00

Charlie Rose Show-- PBS (#1) Human Genome series (MASTER), 2000-06-19T00:00:00+00:00

 Item — Box: MM-27, Object: 16
Identifier: NE0100
Scope and Contents

Charlie Rose Show - Human Genome Series Part 1 with Dr. J. Craig Venter, Dr. Francis Collins, Dr. Hamilton Smith and Marshall Peterson.  Charlie Rose talks to Craig Venter about what the Human Genome Project means, new technologies make the speed of the project possible; how chromosomes and genes work;

Dates: 2000-06-19T00:00:00+00:00

Charlie Rose Show-- PBS (#4) Human Genome series (MASTER), 2000-06-22T00:00:00+00:00

 Item — Box: MM-27, Object: 17
Identifier: NE0101
Scope and Contents

Charlie Rose Show - Human Genome Series Part 4, interview with William Haseltine, Viren Mehta, Nicholas Wade, Richard Preston, and Dr. Caplan.  Potential for better medicine, cures and treatments for diseases coming out of the Human Genome Project; ability to manipulate genes and cells; fight diseases; Nicholas Wade speaks about understanding fruit flies genome, history of Human Genome Project and opposition; mouse genome

Dates: 2000-06-22T00:00:00+00:00

Human Genome Project - CNN Millenium and McLaughlin

 Item — Box: MM-27, Object: 18
Identifier: NE0102
Scope and Contents CNN news report on the Human Genome Project, Francis Collins and Craig Venter profiled as racing towards same goal in a different way.  Collins sees maping genome as goal, Venter sees it as the starting line, explanation of chromosones, DNA, genes; how DNA is deciphered; Collins and Venter show different methods; issues with patenting genetic sequences (Venter's company), while government wants to kepe everything freely available (Collins); Bill Haseltine also supports patents, and is...
Dates: Majority of material found within 1990 - 2010

CNN Medical News (Millenium Coverage Aircheck), 2000-12-01T00:00:00+00:00

 Item — Box: MM-27, Object: 19
Identifier: NE0104
Scope and Contents CNN news feature on mapping the human genome; Francis Collins and Craig Venter methods compared; Collins sees human genome map as goal; Venter sees it as the beginning.  Explanation of DNA, genes, proteins. Genetic diseases and influences on diseases; Collins explains how DNA is read and deciphered; Venter's lab and computers.  Issues of patenting DNA sequences; doctors concerned that protracted legal battles will slow down medical research; court system to decide; Bill Haseltine developing...
Dates: 2000-12-01T00:00:00+00:00

Charlie Rose Show-- PBS (#5) Human Genome series, 2000-06-23T00:00:00+00:00

 Item — Box: MM-27, Object: 20
Identifier: NE0105
Scope and Contents

Charlie Rose Show "Ethics and the Implications of the Human Genome Project" part 5.  Recap of the four previous shows, including clips from all of the scientists that contributed or were interviewed.  

Dates: 2000-06-23T00:00:00+00:00