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Support group meeting of members of Huntington's disease society (people with Huntingtons, caregivers, people at risk, people with family members with Huntingtons) discuss genetic testing for Huntington's, prenatal testing

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Ways to understand genetic components of diseases, locating genes using families with the disease; background and goals of Human Genome project; tie together genetics and patient care

Scope and Contents Educational program about genes - starts with Boomer Esiason talking about child with Cystic fibrosis; explanation of chromosomes; Human Genome Project - Francis Collins speaks about finding genes for diseases through project; gene therapy for Cystic fibrosis; genetic testing - want to know or not; child tested for Familial Adeomatous Polyposis; woman doesn't want to be tested for Huntingtons; Francis Collins speaks about negative affects of genetic testing - loss of insurance or insurance...

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Interview with Jeff Struewing about discovery of BRCA1 gene for inherited forms of breast cancer through the study of Ashkenazi Jewish women; men working in lab and lab equipment

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Topics covered include: simple chemical reactions; central dogma of molecular biology; molecular structures of DNA, RNA and protein enzymes; Ribozymes; chemical examples of catalysis; and catalytc RNA cycle

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Topics covered include: RNA secondary and teriary structure; the Tetrahymena riboyme story; origins of life implications - "Chicken or the egg" dilemma, RNA self-replication, molecular fossil evidence; Medical possiblities - Hammerhead ribozyme targeting, mRNA repair by targeted trans-splicing

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Topics covered include: Group 1 RNA splicing mechanism-transesterification; How much acceleration?; Engineering a true RNA enzyme; Ribozyme as a metalloenzyme; Transition state picture; Three-dimensional model of Michel and Westhof; Testing model by helix extension electon microscopy

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Topics covered include: Telomere functions; Telomere DNA sequences; Why Oxytricha?; The α, β telomere protein story - domain structure, X-ray crystallography; The replication problem - the need for telomerase, the discovery of telomerase by Greider and Blackburn, telomerase has essential RNA component; Cloning the RNA subunit of Oxytricha telomerase; Immunocytochemical localization of telomere protein and telomerase

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Lecture by George Church on Multiplex technologies for genome sequencing and analysis. Technology development in genome sequencing; technology to bring down costs; define multplexing

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Dr Nathan Myhrvold of Microsoft Corporation speaks about "The long-term future of software in Human Genome research" - Introduction by Francis Collins; Myhrvold talks about history of universe, history of information; improvements in computing power and storage