Lecture by Gerald Rubin on "The Drosophila Genome Project: How will it help us to determine the function of human genes?" - Introduction by Francis Collins; why and how are they doing the drosophila genome project; model organisms will help understand how human genes work

Fluorescent In-Situ Hybridization - woman working in lab, microscope and computer, man working at microscope looking at slides

No audio. Male and female scientist in lab looking at gene pairs on transparencies; DNA mapping - computer screens, laboratory equipment operating, man working at microscope in lab; DNA sequencing - man working at computer; three people talking (genetic counseling?)

Interview with young man about his asthma and family history of asthma, participation in genetic study; interview with rest of family about their asthma

Louis Jourdan and John Julius Norwich host documentary - Moods and Music - on manic depressive illness and historic figures

Documentary on breast cancer - genetic causes of breast cancer; hereditary or sporadic damage to genes; carcinogenesis (damage to DNA), promotion (environmental factors that allow genetic factors to be expressed as cancer); mamography; treatments for breast cancer

Genetic counseling session - Doctor speaking to patient about possibility of getting Huntington's disease and having genetic testing; uncertainty of not knowing; Man discussing method for predictive testing for Huntington's, all the exams patients undergo - physical and psychological, symptoms of Huntington's

Woman being tested for Huntington's disease symptoms (shows woman's face, then shots of the blocks being used for the test); Female scientist doing lab work explains what she's doing (separating red and white blood cells), putting vials of blood in the centrifuge, at computer showing image of PCR fragments

Female scientist talking about how DNA is extracted from blood, looking at fragment of gene to find Huntington's disease fragments; explanation of genetic mutation and how it works; how fragments are separated; Male scientist working in a lab and close ups

Human Genome Database - images of computer screens; Linus 3D modeling of protein structures computer screens; close up of hand manipulating computer mouse and typing on keyboard; George Rose, professor at Johns Hopkins Biophysics Dept - predict 3D structure of proteins from linear structure of amino acids; how proteins are related to Human Genome Project by making 3D information available of each protein in the genome, important because proteins do chemistry with their shape